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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
IHC-00623-T | 10 µl (2500 ng) | - |
2 - 8 business days* |
164.00€
|
|||
IHC-00623 | 100 µl (25 µg) | - |
2 - 8 business days* |
623.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Component of the CCR4-NOT complex which is one of the major cellular mRNA... more
Product information "Anti-CNOT3 (IHC)"
Protein function: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation, may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem (ES) cell identity. [The UniProt Consortium]
Keywords: | Anti-CNOT3, Anti-KIAA0691, Anti-CCR4-associated factor 3, Anti-Leukocyte receptor cluster member 2, Anti-CCR4-NOT transcription complex subunit 3 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | IHC-00623 |
Properties
Application: | IHC, IHC-IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: dog, orangutan, rhesus monkey, gorilla, chimpanzee, nine-banded armadillo, crab-eating macaque, olive baboon, gray short-tailed opossum, small-eared galago, greater horseshoe bat) |
Immunogen: | synthetic peptide. The epitope recognized by IHC-00623 maps to a region between residue 525 and 575 of human CCR4-NOT transcription complex, subunit 3 using the numbering given in entry NP_055331.1 (GeneID 4849). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K12580 | Matching products |
UniProt ID : | O75175 | Matching products |
Gene ID | GeneID 4849 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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