Protein function: DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding. [The UniProt Consortium]
Anti-ALC1, Anti-CHD1L, EC=220.127.116.11, Anti-Amplified in liver cancer protein 1, Anti-Chromodomain-helicase-DNA-binding protein 1-like
synthetic peptide. The epitope recognized by A303-343A-T maps to a region between residue 847 and 897 of human Chromodomain Helicase DNA Binding Protein 1-Like using the numbering given in entry NP_004275.3 (GeneID 9557).