Anti-CDC2L5

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-458A-T	10 µl (2 µg)		-		2 - 8 business days*		164.00€
A301-458A	100 µl		-		2 - 8 business days*		588.00€

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Protein function: Cyclin-dependent kinase which displays CTD kinase activity and is required for... more

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Product information "Anti-CDC2L5"

Protein function: Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys- 51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef. [The UniProt Consortium]

Keywords:	Anti-CDC2L, Anti-CDK13, Anti-hCDK13, EC=2.7.11.22, EC=2.7.11.23, Anti-Cyclin-dependent kinase 13, Anti-CDC2-related protein kinase 5, Anti-Cell division protein kinase 13, Anti-Cell division cycle 2-like protein kinase 5
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-458A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, bovine)
Immunogen:	synthetic peptide. The epitope recognized by A301-458A-T maps to a region between residue 1125 and 1175 of human cell division cycle 2-like 5 using the numbering given in entry NP_003709.3 (GeneID 8621).
Format:	Antigen Affinity Purified