Anti-CD86

Anti-CD86
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030066.100 100 µl - -

3 - 19 business days*

477.00€
 
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily.... more
Product information "Anti-CD86"
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined.Tissue specificity: Expressed by activated B-lymphocytes and monocytes. Applications: Western Bloting: 1:500-1:2000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-B70, Anti-BU63, Anti-CD86, Anti-FUN-1, Anti-CD28LG2, Anti-Activation B7-2 antigen, Anti-CTLA-4 counter-receptor B7.2, Anti-T-lymphocyte activation antigen CD86
Supplier: United States Biological
Supplier-Nr: 030066

Properties

Application: ELISA, WB
Antibody Type: Monoclonal
Clone: 13B144
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of human CD86 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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