Anti-CD80 / B7-1, clone C80/1608

Anti-CD80 / B7-1, clone C80/1608
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3297-20UG 20 µg - -

3 - 10 business days

251.00€
NSJ-V3297-100UG 100 µg - -

3 - 10 business days

541.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. T cell proliferation... more
Product information "Anti-CD80 / B7-1, clone C80/1608"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell. Protein function: Involved in the costimulatory signal essential for T- lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation. [The UniProt Consortium]
Keywords: Anti-B7, Anti-BB1, Anti-CD80, Anti-CD28LG, Anti-Activation B7-1 antigen, Anti-CTLA-4 counter-receptor B7.1, Anti-T-lymphocyte activation antigen CD80, CD80 Antibody / B7-1
Supplier: NSJ Bioreagents
Supplier-Nr: V3297-20UG

Properties

Application: FC, IF, ELISA (protein)
Antibody Type: Monoclonal
Clone: C80/1608
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant human protein used as the immunogen for the CD80 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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