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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-30-1333-0.1 | 100 µg | - |
3 - 11 business days* |
580.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The CD66e (CEA, 180-200 kDa) is a member of carcinoembryonic antigens, immunoglobulin supergene... more
Product information "Anti-CD66e / CEA Monoclonal Antibody (Clone:CB30)"
The CD66e (CEA, 180-200 kDa) is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3). Human CD66e is heavily glycosylated GPI anchored protein capable of both homophilic and heterophilic adhesion.Disease relevance: The CD66e may play a role in the process of metastasis of cancer cells. CD66e is found in serum and it is clinically used as a tumor marker for early detection of disease due to its expression in adenocarcinomas - potential target of tumor imaging and drug targeting. Protein function: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression, induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050). [The UniProt Consortium]
Keywords: | Anti-CEA, Anti-CD66e, Anti-CEACAM5, Anti-Meconium antigen 100, Anti-Carcinoembryonic antigen, Anti-Carcinoembryonic antigen-related cell adhesion molecule 5, Anti-CD66e / CEA Monoclonal Antibody (Clone:CB30) |
Supplier: | Abeomics |
Supplier-Nr: | 30-1333 |
Properties
Application: | FC, IP, IHC, IHC (frozen) |
Antibody Type: | Monoclonal |
Clone: | CB30 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Human carcinoembryonic antigen (CEA, CEACAM5) |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06499 | Matching products |
UniProt ID : | P06731 | Matching products |
Gene ID | GeneID 1048 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
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