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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R20390-0.1ML | 100 µl | - | - |
3 - 10 business days* |
737.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. This antibody reacts to human... more
Product information "Anti-CD163, clone RM371"
Antibody in PBS with 50% glycerol, 1% BSA and 0.09% sodium azide. This antibody reacts to human CD163. Protein function: Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH- dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells. [The UniProt Consortium]
Keywords: | Anti-M130, Anti-CD163, CD163 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R20390 |
Properties
Application: | WB, IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | RM371 |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | peptide corresponding to the N-terminus of human CD163 |
Format: | Purified |
Database Information
KEGG ID : | K06545 | Matching products |
UniProt ID : | Q86VB7 | Matching products |
Gene ID | GeneID 9332 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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