Anti-CCR3 (Chemokine Receptor 3, CC-CCR-3, CKR3)

Anti-CCR3 (Chemokine Receptor 3, CC-CCR-3, CKR3)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C2099-85B.40 40 µg - -

3 - 19 business days*

346.00€
 
CCR3 is a member of the seven transmembrane G-protein coupled receptor (GPCR) family, and is a... more
Product information "Anti-CCR3 (Chemokine Receptor 3, CC-CCR-3, CKR3)"
CCR3 is a member of the seven transmembrane G-protein coupled receptor (GPCR) family, and is a high affinity chemokine receptor for the chemokines eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26) and MCP-4 (CCL13). In addition, it has been reported to bind RANTES, MCP-3 and MCP-4. CCR3 has been shown to exist in blood, brain, lung, bone marrow, kidney, liver, lymph node, placenta, skin, spleen, thymus, thyroid, uterus, and vessel. The agonists for CXCR3 (IP-10, mig, and I-TAC) act as antagonists for CCR3 by competing for the binding of eotaxin to CCR3. CCR3 likely plays an important role in the migration of eosinophils in allergic airway inflammation and asthma. Meanwhile, CCR3 can also serve as a receptor for HIV-1 cell entry. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.05-0.2ug/ml, Immunohistochemistry: 5-10ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-CCR3, Anti-CKR3, Anti-CD193, Anti-CCR-3, Anti-CMKBR3, Anti-CC-CKR-3, Anti-C-C CKR-3, Anti-Eosinophil eotaxin receptor, Anti-C-C chemokine receptor type 3
Supplier: United States Biological
Supplier-Nr: C2099-85B

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide derived from the N-terminal extracellular domain of human CCR3.
Purity: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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