Anti-CBP

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A300-363A-T	10 µl (10 µg)		-		2 - 8 business days*		178.00€
A300-363A	100 µl (100 µg)		-		2 - 8 business days*		630.00€

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Protein function: Acetylates histones, giving a specific tag for transcriptional activation. Also... more

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Product information "Anti-CBP"

Protein function: Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK- ARNTL/BMAL1 heterodimers. Acetylates PCNA, acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902). [The UniProt Consortium]

Keywords:	Anti-CBP, Anti-CREBBP, Anti-CREB-binding protein
Supplier:	Bethyl Laboratories
Supplier-Nr:	A300-363A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, small-eared galago, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A300-363A-T maps to a region between residues 2375 and 2425 of human CREB Binding Protein using the numbering given in entry NP_004371.1 (GeneID 1387).
Format:	Antigen Affinity Purified