Anti-Caspase 10 (FLICE2, Mch4)

Anti-Caspase 10 (FLICE2, Mch4)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
C2088-44A.40 40 µg - -

3 - 19 business days*

346.00€
 
Caspase 10 belongs to the peptidase C14A family. It is involved in the caspase activation cascade... more
Product information "Anti-Caspase 10 (FLICE2, Mch4)"
Caspase 10 belongs to the peptidase C14A family. It is involved in the caspase activation cascade and the execution of apoptosis. Caspase 10 is recruited to both Fas- and TNFR-1 receptors in a FADD-dependent manner. Caspase 10 may participate in the granzyme B apoptotic pathways. It cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Four isoforms of caspase 10 (caspase 10a, 10b, 10c, and 10d) have been described to date. These isoforms all have the same prodomain but different mature large and small subdomains. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.05-0.2ug/ml, Western Blot: 0.5-1ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute by adding sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20ºC. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-CASP10, EC=3.4.22.63, Anti-CASP-10, Anti-Caspase-10, Anti-Caspase-10 subunit p12, Anti-Apoptotic protease Mch-4, Anti-Caspase-10 subunit p23/17, Anti-ICE-like apoptotic protease 4
Supplier: United States Biological
Supplier-Nr: C2088-44A

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: Synthetic peptide from residues 169-219 of human caspase 10 protein (Swiss Prot: Q92851). (KLH coupled)
Purity: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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