Anti-CAR

Anti-CAR
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-848A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A302-848A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A302-848A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Component of the epithelial apical junction complex that may function as a... more
Product information "Anti-CAR"
Protein function: Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. [The UniProt Consortium]
Keywords: Anti-CAR, Anti-hCAR, Anti-CXADR, Anti-HCVADR, Anti-CVB3-binding protein, Anti-Coxsackievirus B-adenovirus receptor, Anti-Coxsackievirus and adenovirus receptor
Supplier: Bethyl Laboratories
Supplier-Nr: A302-848A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Mouse, Rat, Bovine, Orangutan)
Immunogen: synthetic peptide. The epitope recognized by A302-848A-T maps to a region between residue 335 and 365 of human Coxsackievirus and Adenovirus Receptor Protein using the numbering given in entry NP_001329.1 (GeneID 1525).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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