Anti-CXADR / CAR

Anti-CXADR / CAR
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG58453.100 100 µl - -

6 - 14 business days*

624.00€
 
Protein function: Component of the epithelial apical junction complex that may function as a... more
Product information "Anti-CXADR / CAR"
Protein function: Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. [The UniProt Consortium]
Keywords: Anti-CAR, Anti-hCAR, Anti-CXADR, Anti-HCVADR, Anti-CVB3-binding protein, Anti-Coxsackievirus B-adenovirus receptor, Anti-Coxsackievirus and adenovirus receptor
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG58453

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse
Immunogen: Recombinant funsion protein corresponding to aa. 20-237 of Human CXADR / CAR (NP_001329.1)
MW: 40 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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