Anti-BLM / Blooms Syndrome Protein

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG66736.100	100 µg		-	-	6 - 14 business days*		624.00€

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Protein function: ATP-dependent DNA helicase that unwinds single- and double- stranded DNA in a... more

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Product information "Anti-BLM / Blooms Syndrome Protein"

Protein function: ATP-dependent DNA helicase that unwinds single- and double- stranded DNA in a 3'-5' direction (PubMed:9388193, PubMed:24816114, PubMed:25901030). Participates in DNA replication and repair (PubMed:12019152, PubMed:21325134, PubMed:23509288). Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA (PubMed:21325134). Negatively regulates sister chromatid exchange (SCE) (PubMed:25901030). Stimulates DNA 4-way junction branch migration and DNA Holliday junction dissolution (PubMed:25901030). Binds single- stranded DNA (ssDNA), forked duplex DNA and DNA Holliday junction (PubMed:20639533, PubMed:24257077, PubMed:25901030). [The UniProt Consortium]

Keywords:	Anti-BLM, Anti-RecQ2, Anti-RECQ2, Anti-RecQ protein-like 3, Anti-Bloom syndrome protein, Anti-DNA helicase, RecQ-like type 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG66736

Properties

Application:	ICC, IF, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Synthetic peptide between aa. 65-114 of Human BLM / Blooms Syndrome Protein
MW:	159 kD
Format:	Antigen Affinity Purified