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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-35-1416-100 | 100 µg | - |
3 - 11 business days* |
682.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known... more
Product information "Anti-BAD (Ab-112)"
The protein encoded by BAD gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. Protein function: Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways. [The UniProt Consortium]
Keywords: | Anti-BAD, Anti-Bad, Anti-Bbc6, Anti-Bcl-2-binding component 6, Anti-Bcl2 antagonist of cell death, Anti-Bcl2-associated agonist of cell death, Anti-Bcl-xL/Bcl-2-associated death promoter, Polyclonal Antibody to BAD (Ab-112) |
Supplier: | Abeomics |
Supplier-Nr: | 35-1416 |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Peptide sequence around aa.110~114 (H-S-S-Y-P) derived from Mouse BAD. |
Format: | Purified |
Database Information
KEGG ID : | K02158 | Matching products |
UniProt ID : | Q61337 | Matching products |
Gene ID | GeneID 12015 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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