Protein function: Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration. [The UniProt Consortium]
Anti-PAP, Anti-PAG3, Anti-ASAP2, Anti-DDEF2, Anti-Pyk2 C-terminus-associated protein, Anti-Development and differentiation-enhancing factor 2, Anti-Paxillin-associated protein with ARF GAP activity 3, Anti-Arf-GAP with SH3 domain
Human (Expected: Horse, Orangutan, Gorilla, Chimpanzee, Northern White-cheeked Gibbon)
synthetic peptide. The epitope recognized by A303-311A-T maps to a region between residue 900 and 950 of human ArfGAP with SH3 domain, Ankyrin Repeat and PH Domain 2 using the numbering given in entry NP_003878.1 (GeneID 8853).