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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A304-550A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A304-550A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Acts as a mediator between the cap-binding complex (CBC) and the primary... more
Product information "Anti-ARS2"
Protein function: Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA), however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription. [The UniProt Consortium]
Keywords: | Anti-ARS2, Anti-SRRT, Anti-Arsenite-resistance protein 2, Anti-Serrate RNA effector molecule homolog |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A304-550A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse (Expected: zebrafish, X. laevis, bovine, orangutan) |
Immunogen: | synthetic peptide. The epitope recognized by A304-550A-T maps to a region between residue 1 to 50 of human Arsenate Resistance Protein 2 using the numbering given in entry NP_056992.4 (GeneID 51593). |
Format: | Antigen Affinity Purified |
Database Information
UniProt ID : | Q9BXP5 | Matching products |
Gene ID | GeneID 51593 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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