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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A1372-31H5.50 | 50 µg | - | - |
3 - 19 business days* |
1,060.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
AMICA, also known as junctional adhesion molecule-like protein (JAML), is a 60kD type I... more
Product information "Anti-AMICA (Adhesion Molecule that Interacts with CXADR Antigen 1, Junction Adhesion Molecule-Like,"
AMICA, also known as junctional adhesion molecule-like protein (JAML), is a 60kD type I transmembrane glycoprotein in the CTX (cortical thymocyte marker in Xenopus) family of adhesion molecules. Like other CTX family proteins, AMICA has an extracellular domain containing one V- and one C-type Ig domain, a transmembrane domain and an intracellular tail that lacks a PDZ-binding motif. AMICA is expressed on neutrophils and participates in heterophilic adhesive interactions with CXADR at tight junctions of polarized epithelia. Two additional isoforms that differ either in the signal peptide or contain substitutions in residues 258 and 259, have been reported. Within their extracellular domains, human and mouse AMICA share approximately 55% aa sequence homology. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: ELISA (Detection): 0.1-0.4ug/ml can be used as a detection reagent in a human AMICA sandwich immunoassay in combination with the human AMICA capture reagent (A1372-31H4) and recombinant human AMICA as the standard. Shows <0.3% crossreactivity with recombinant mouse AMICA and recombinant human JAM-A, JAM-B and JAM-C., Western Blot: 0.1-0.2ug/ml. The detection limit is ~5ng/lane under non-reducing and reducing conditions., Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile TBS, 0.1% BSA. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-AMICA1, Anti-Junctional adhesion molecule-like, Anti-Dendritic cell-specific protein CREA7-1, Anti-Adhesion molecule interacting with CXADR antigen 1 |
Supplier: | United States Biological |
Supplier-Nr: | A1372-31H5 |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | Biotin |
Host: | Goat |
Species reactivity: | human |
Immunogen: | Purified, NS0-derived, recombinant human AMICA. |
Database Information
UniProt ID : | Q86YT9 | Matching products |
Gene ID | GeneID 120425 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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