Anti-AMICA (Adhesion Molecule that Interacts with CXADR Antigen 1, Junction Adhesion Molecule-Like,

Anti-AMICA (Adhesion Molecule that Interacts with CXADR Antigen 1, Junction Adhesion Molecule-Like,
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A1372-31H.100 100 µg - -

3 - 19 business days*

916.00€
 
AMICA is a 60kD type I transmembrane glycoprotein member of the JAM family of adhesion molecules.... more
Product information "Anti-AMICA (Adhesion Molecule that Interacts with CXADR Antigen 1, Junction Adhesion Molecule-Like,"
AMICA is a 60kD type I transmembrane glycoprotein member of the JAM family of adhesion molecules. Human AMICA has an extracellular domain (ECD) of 275aa and a cytoplasmic tail of 98aa. The ECD contains two Ig-like regions. There is an N-terminal C2-type Ig-like domain and a membrane proximal V-type Ig-like domain. AMICA is expressed by leukocytes and is concentrated at areas of cell-cell contact. It forms noncovalent homodimers on the cell surface and binds CXADR on epithelial cells. Two splice variants apparently exist that only involve the first 40aa of the precursor. Human AMICA ECD is 62% and 76% aa identical to mouse and dog AMICA ECD, respectively. Applications: Suitable for use in Flow Cytometry, ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Flow Cytometry: 2.5ug/ml/10e6 cells using human whole blood monocytes., Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: Anti-AMICA1, Anti-Junctional adhesion molecule-like, Anti-Dendritic cell-specific protein CREA7-1, Anti-Adhesion molecule interacting with CXADR antigen 1
Supplier: United States Biological
Supplier-Nr: A1372-31H

Properties

Application: ELISA, FC, WB
Antibody Type: Monoclonal
Clone: 8H172
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: NS0-derived rhAMICA (aa10-265)
Format: Affinity Purified

Database Information

UniProt ID : Q86YT9 | Matching products
Gene ID GeneID 120425 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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