Anti-aldehyde dehydrogenase family 5, member A1 (Aldh5A1, NAD(+)-dependent succinic semialdehyde deh

Anti-aldehyde dehydrogenase family 5, member A1 (Aldh5A1, NAD(+)-dependent succinic semialdehyde deh
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A1334-36M.100 100 µg - -

3 - 19 business days*

511.00€
 
Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent... more
Product information "Anti-aldehyde dehydrogenase family 5, member A1 (Aldh5A1, NAD(+)-dependent succinic semialdehyde deh"
Aldh5A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldehyde dehydrogenase enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Aldh5A1 is a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, results in a disorder of the neurotransmitter 4-aminobutyric acid (GABA). Symptoms usually include static encephalopathy, associated with developmental delays, hypotonia, ataxia, speech defects, and seizures. At least two isoforms of Aldh5A1 are known to exist. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-2ug/ml, Optimal dilutions to be determined by the researcher. Positive Control: Mouse Liver Tissue Lysate, Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: EC=1.2.1.24, Anti-Aldehyde dehydrogenase family 5 member A1, Anti-Succinate-semialdehyde dehydrogenase, mitochondrial
Supplier: United States Biological
Supplier-Nr: A1334-36M

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide corresponding to 22aa from near the carboxy terminus of the human Aldh5A1.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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