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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABE-12-1063-20 | 20 µg | - |
3 - 11 business days* |
373.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
AIF1 is a cytoplasmic, calcium-binding protein that is thoµght to play a role in macrophage... more
Product information "Anti-AIF1 / Iba1 (Microglia Marker) Recombinant Mouse Monoclonal Antibody (clone:rAIF1/1909)"
AIF1 is a cytoplasmic, calcium-binding protein that is thoµght to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC). Protein function: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T- lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. [The UniProt Consortium]
Keywords: | Anti-G1, Anti-AIF1, Anti-AIF-1, Anti-Protein G1, Anti-Allograft inflammatory factor 1, Anti-Ionized calcium-binding adapter molecule 1, Anti-AIF1 / Iba1 (Microglia Marker) Recombinant Mouse Monoclonal Antibody (Clone:rAIF1/1909) |
Supplier: | Abeomics |
Supplier-Nr: | 12-1063-20 |
Properties
Application: | IHC, Protein Array |
Antibody Type: | Monoclonal |
Clone: | rAIF1/1909 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Purified recombinant human AIF1 protein (around aa 1-146) (exact sequence is proprietary) |
Format: | Purified |
Database Information
KEGG ID : | K18617 | Matching products |
UniProt ID : | P55008 | Matching products |
Gene ID | GeneID 199 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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You will get a certificate here
-30 %
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-30 %
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