Anti-Adiponectin, clone ADPQ-1

Anti-Adiponectin, clone ADPQ-1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V7249SAF-100UG 100 µg - -

3 - 10 business days*

578.00€
 
1 mg/ml in sterile PBS, BSA free, sodium azide free. Adiponectin (commonly called ADIPO, or by... more
Product information "Anti-Adiponectin, clone ADPQ-1"
1 mg/ml in sterile PBS, BSA free, sodium azide free. Adiponectin (commonly called ADIPO, or by the gene name ADIPOQ) is an adipocytokine, a hormone produced in adipose tissue. It is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma ADIPO levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women, levels tend to be higher than in men, which may be due to androgens suppressing ADIPO levels. Furthermore, adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low ADIPO levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism. Protein function: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. [The UniProt Consortium]
Keywords: Anti-ACDC, Anti-apM-1, Anti-ADIPOQ, Anti-ACRP30, Anti-Adiponectin, Anti-Gelatin-binding protein, Anti-Adipocyte complement-related 30 kDa protein, Anti-30 kDa adipocyte complement-related protein, Anti-Adipose most abundant gene transcript 1 protein, Adip
Supplier: NSJ Bioreagents
Supplier-Nr: V7249SAF

Properties

Application: ELISA, FC, IF, IHC
Antibody Type: Monoclonal
Clone: ADPQ-1
Conjugate: No
Host: Mouse
Reactivity: Human. Others Not Tested
Immunogen: A human partial recombinant protein was used as the immunogen for this Adiponectin antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-Adiponectin, clone ADPQ-1"
Write a review
or to review a product.
Viewed