Anti-Adiponectin

Anti-Adiponectin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-G72 100 µg - -

6 - 10 business days*

684.00€
 
Anti-Adiponectin Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-Adiponectin"
Anti-Adiponectin Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with Adiponectin with Human, Mouse and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with Adiponectin from other sources has not been determined. Adiponection antibody detects human adiponectin. Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike the CTRPs, which are expressed in a wide variety of tissues, adiponectin is reported to be expressed exclusively by differentiated adipocytes. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. It is present in high levels in normal human plasma, but is reduced in obese subjects and often in those with increased insulin resistance and type 2 diabetes, suggesting that adiponectin may be a useful pharmacological target in various metabolic diseases. Anti-Adiponectin antibodies are ideal for investigators involved in glucose engery metabolism and apolipoprotein research.
Keywords: Anti-APM1, Anti-ACDC, Anti-apM-1, Anti-GBP28, Anti-ACRP30, Anti-ADIPOQ, Anti-Adiponectin, Anti-Gelatin-binding protein, Anti-Adipocyte complement-related 30 kDa protein, Anti-30 kDa adipocyte complement-related protein
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-G72

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: peptide from near the c-terminus of human adiponectin.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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