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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A0859-10F.20 | 20 µl | - | - |
3 - 19 business days* |
462.00€
|
||
A0859-10F.100 | 100 µl | - | - |
3 - 19 business days* |
826.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The ADAM (A Disintegrin and A Metalloprotease) family of multidomain membrane proteins influences... more
Product information "Anti-ADAM 9 (A Disintegrin and Metalloproteinase Domain 9, ADAM Metallopeptidase Domain 9, ADAM9, AD"
The ADAM (A Disintegrin and A Metalloprotease) family of multidomain membrane proteins influences cell signaling and adhesion by shedding cell surface proteins such as cytokines and growth factors, by influencing cell adhesion to the extracellular matrix (ECM), and by directly remodeling the ECM. Conserved domains in ADAM family members include a prodomain, a zinc-dependent metalloprotease domain, a disintegrin domain, a cysteine-rich domain, an EGF-like sequence and a short cytoplasmic tail (1,2). The prodomain is thought to aid in protein folding. Disintegrin and cysteine-rich domains mediate adhesion at least in part through binding to integrins. Phosphorylation of the cytoplasmic tail as well as its interaction with other signaling proteins may influence intra- and extracellular signaling (1). ADAM9 is widely distributed and has been shown to affect migration in skin keratinocytes (3,4). ADAM9 is overexpressed in prostate cancer (5), pancreatic cancer (6), gastric cancer (7) and has been linked to invasion and metastasis in small cell lung cancer (8). An alternatively spliced short (50kD) form of ADAM9 containing protease activity is involved in tumor cell invasion (9). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000, incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight. , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-MDC9, Anti-MCMP, Anti-MLTNG, Anti-ADAM9, Anti-ADAM 9, EC=3.4.24.-, Anti-KIAA0021, Anti-Meltrin-gamma, Anti-Myeloma cell metalloproteinase, Anti-Cellular disintegrin-related protein, Anti-Metalloprotease/disintegrin/cysteine-rich protein 9 |
Supplier: | United States Biological |
Supplier-Nr: | A0859-10F |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | 10g134(D64B5) |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, monkey, mouse, rat |
Immunogen: | Synthetic peptide corresponding to residues near the carboxy terminus of human ADAM9. |
Format: | Supernatant |
Database Information
KEGG ID : | K06834 | Matching products |
UniProt ID : | Q13443 | Matching products |
Gene ID | GeneID 8754 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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