Anti-Activin B

Activin B is a TGF-b family member that exhibits a wide range of biological activities including regulation of embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands. Activin B, like certain other members of the TGF-b family, signals through the ActRII receptor (Activin Receptor type II). Human Activin B is a 26.0kD disulfide-linked homodimer consisting of two bB chains, each containing 115 amino acid residues. Applications: Suitable for use in Neutralization, ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml, Neutralization: 0.6-3ug/ml in the presence of 7.5ng/ml recombinant human Activin B, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.