Kisspeptin-10 (mouse, rat)

Kisspeptin-10 is a neuropeptide and ligand of the kisspeptin receptor, previously known as G protein-coupled receptor 54 (GPR54). It corresponds to amino acids 110-119 of rodent kisspeptin-1 (KiSS1), a metastasis suppressor gene product. Kisspeptin-10 (10 µM) inhibits FGF2-induced migration of NIH3T3 cells expressing the mouse kisspeptin receptor. Intracerebroventricular administration of kisspeptin-10 increases serum follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels in adult male rats (ED50s = 400 and 4 pmol/animal).Formal Name: L-tyrosyl-L-asparaginyl-L-tryptophyl-L-asparaginyl-L-seryl-L-phenylalanylglycyl-L-leucyl-L-arginyl-L-tyrosinamide. CAS Number: 478507-53-8. Synonyms: Kp-10, YNWNSFGLRY-NH2. Molecular Formula: C63H83N17O15. Formula Weight: 1318.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Water: soluble. SMILES: O=C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@H](C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC1=CC=C(O)C=C1)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)[C@@H](NC([C@H](CC(N)=O)NC([C@@H](N)CC3=CC=C(O)C=C3)=O)=O)CC4=CNC5=CC=CC=C45. InChi Code: InChI=1S/C63H83N17O15/c1-33(2)23-45(58(91)74-43(13-8-22-70-63(68)69)57(90)75-44(54(67)87)25-36-16-20-39(83)21-17-36)73-53(86)31-72-56(89)46(26-34-9-4-3-5-10-34)77-62(95)50(32-81)80-61(94)49(29-52(66)85)79-59(92)47(27-37-30-71-42-12-7-6-11-40(37)42)78. InChi Key: HVPGTDOCSYBNFC-INXYWQKQSA-N.