Calpeptin

Calpeptin is a cell-penetrating peptide inhibitor of calpain (IC50 = 5 nM) which completely abolishes calpain activity in platelets. In this way, it inhibits both collagen- and thrombin-induced aggregation of platelets. Calpeptin is also a potent inhibitor of cathepsin K (IC50 = 0.11 nM).Formal Name: N-[(1S)-1-[[[(1S)-1-formylpentyl]amino]carbonyl]-3-methylbutyl]-carbamic acid, phenylmethyl ester. CAS Number: 117591-20-5. Molecular Formula: C20H30N2O4. Formula Weight: 362.5. Purity: >90%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml. SMILES: O=C(N[C@@H](CC(C)C)C(N[C@@H](CCCC)C([H])=O)=O)OCC1=CC=CC=C1. InChi Code: InChI=1S/C20H30N2O4/c1-4-5-11-17(13-23)21-19(24)18(12-15(2)3)22-20(25)26-14-16-9-7-6-8-10-16/h6-10,13,15,17-18H,4-5,11-12,14H2,1-3H3,(H,21,24)(H,22,25)/t17-,18-/m0/s1. InChi Key: PGGUOGKHUUUWAF-ROUUACIJSA-N.