Other Peptides

3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...

Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...

Tentoxin is a cyclic tetrapeptide first isolated from the plant pathogen A. alternata. It is an herbicide that inhibits chloroplast development, resulting in chlorotic tissue. Tentoxin is selectively phytotoxic, as it kills a number of important weeds at concentrations that have no effects on several important...

Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...

MDM2 (32-46) is a peptide fragment of MDM2. Formal Name: ((S)-2-formylpyrrolidin-1-yl)-L-leucyl-L-leucyl-L-leucyl-L-lysyl-L-leucyl-L-leucyl-L-lysyl-L-seryl-L-valylglycyl-L-alanyl-L-glutaminyl-L-lysyl-L-aspartic acid, trifluoroacetate salt. Molecular Formula: C75H135N19O20  XCF3COOH. Formula Weight: 1623.0. Purity:...

HBP08 is a peptide inhibitor of the protein-protein interaction between chemokine (C-X-C motif) ligand 12 (CXCL12) and high mobility group protein B1 (HMGB1). It binds to HMGB1 (Kd = 0.8 µM) and inhibits HMGB1-induced inhibition of CXCL12-induced migration of 300-19 pre-B cells expressing human chemokine (C-X-C...

[Gly8,36,Glu22]-Glucagon-like peptide 1 ([Gly8,36,Glu22]-GLP-1) (7-37) is a derivative of GLP-1 containing alanine-to-glycine, glycine-to-glutamate, and arginine-to-glycine substitutions at positions 8, 22, and 36, respectively, and a peptide fragment of the GLP-1 receptor (GLP-1R) agonist dulaglutide.Formal Name:...

Myristoyl hexapeptide-16 is a myristoylated form of the hexapeptide Leu-Lys-Lys-Ala-Leu-Lys. An acid form of myristoyl hexapeptide-16 is active against E. coli, P. aeruginosa, S. aureus, and methicillin-resistant S. aureus (MRSA, MICs = =100 ppm for all).Formal Name:...

Enramycin A is a lipopeptide antibiotic that has been found in S. fungicidicus. It also inhibits avian myeloblastosis virus reverse transcriptase by 50% when used at a concentration of 10 µg/ml in a cell-free assay. Formulations containing enramycin A have been used as feed additives to prevent bacterial necrotic...

Mechercharmycin A is a cyclic peptide originally isolated from Thermoactinomyces that has anticancer activity. It induces cytotoxicity in A549 lung cancer and Jurkat leukemia cells (IC50s = 40 and 46 nM, respectively).Formal Name:...

Synthetic Strep-tag(R)II peptide recognized by Strep-Tactin(R), Strep-Tactin(R)XT as well as the monoclonal antibodies, StrepMAB-Classic and StrepMAB-Immo. It can be used for competitive elution of Strep-tag(R)II fusion proteins or as control protein in dot blot assays.

Sulfo-SMCC is a water-soluble protein cross-linking reagent that contains an anime-reactive sulfo-N-hydroxysuccinimide (sulfo-NHS) ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. It has been used to conjugate anti-programmed cell death ligand 1 (PD-L1) antibodies to...