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Item number: Cay35899-1
Atogepant is an antagonist of the calcitonin gene-related peptide (CGRP) receptor (IC50 = 0.026 nM). It is selective for the CGRP receptor over the adrenomedullin receptors (AM1) and AM2, calcitonin (CT) receptor, amylin receptor 1 (AMY1), and AMY3 receptor (IC50s = >18,000, 400, 6,274, 2.4 and 1,418 nM,...
Keywords: | (3'S)-1',2',5,7-tetrahydro-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-... |
Application: | CGRP receptor (CALCRL) antagonist |
CAS | 1374248-81-3 |
MW: | 603.5 D |
409.00€
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Item number: Cay38850-10
KEMPFPKYPVEP Peptide is a peptide fragment of the dairy protein beta-casein. It can be produced by the protease M from A. oryzae and is found in dairy products fermented by fungi but not bacteria. KEMPFPKYPVEP Peptide (2 mg/kg) increases the levels of dopamine, norepinephrine, and homovanillic acid, but not...
Keywords: | L-lysyl-L-alpha-glutamyl-L-methionyl-L-prolyl-L-phenylalanyl-L-prolyl-L-lysyl-L-tyrosyl-L-prolyl-L-valyl-L-alpha-glutamyl-... |
Application: | Beta-casein peptide fragment |
MW: | 1461.7 D |
From 34.00€
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Item number: Cay39723-1
Bradykinin (2-9) is a metabolite of the endogenous vasodilator peptide bradykinin (Cay-37408). It is formed from bradykinin via N-terminal cleavage by carboxypeptidase.Synonyms: BK (2-9), (Des-Arg1)-BK, (Des-Arg1)-Bradykinin, H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH. Molecular Formula: C44H61N11O10 . XCF3COOH. Formula...
Keywords: | (Des-Arg1)-BK, (Des-Arg1)-Bradykinin, BK (2-9), H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH, (Des-Arg1)-BDK |
Application: | Bradykinin metabolite |
MW: | 904 D |
From 61.00€
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Item number: Cay39725-1
Heparin-binding peptide is a synthetic peptide fragment corresponding to residues 1,892-1,899 of the C-terminal heparin-binding domain of fibronectin. It induces focal adhesion formation in pre-spread human embryonic fibroblasts (HEFs) when used at concentrations ranging from 1 to 1,000 µg/ml. Heparin-binding...
Keywords: | Fibronectin Adhesion-promoting Peptide, Fibronectin Peptide V, FN-C/H-V,... |
Application: | Fibronectin peptide fragment |
MW: | 1023.2 D |
From 34.00€
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Item number: Cay39727-1
Kassinin is a tachykinin neuropeptide and agonist of the neurokinin-2 (NK2) and NK3 receptors. It is selective for the NK2 and NK3 receptors over the NK1 receptor. Kassinin (1 µM) increases the short-circuit current in isolated frog skin. It induces contractions in isolated guinea pig ileum and isolated rabbit...
Application: | Tachykinin neuropeptide |
MW: | 1334.6 D |
From 88.00€
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Item number: Cay39728-1
Buccalin A is a neuropeptide that is found in gastropod motor neurons and is involved in neuromuscular signaling. It reduces current-induced muscle contraction amplitude but not muscle relaxation rate in isolated and washed A. californica accessory radula closer (ARC) muscle fibers when used at a concentration of 10...
Keywords: | (3S,6S,9S,12S,15S,18S,27S)-3-((S)-2-(2-aminoacetamido)-4-(methylthio)butanamido)-15-benzyl-27-carbamoyl-6,18-bis(hydroxyme... |
Application: | Neuropeptide |
MW: | 1053.2 D |
From 39.00€
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Item number: Cay40142-1
PF-05190457 is an inverse agonist of the growth hormone secretagogue receptor (GHS-R), which is also known as the ghrelin receptor. It selectively binds to GHS-R (Ki = 4.37 nM) over M2 muscarinic acetylcholine receptors (mAChRs, Ki = 1,950 nM) and the serotonin (5-HT) receptor subtype 5-HT2B (IC50 = 3,700 nM)....
Keywords: | 1-[2-[(1R)-2,3-dihydro-5-(6-methyl-4-pyrimidinyl)-1H-inden-1-yl]-2,7-diazaspiro[3.5]non-7-yl]-2-(2-methylimidazo[2,1-b]thi... |
Application: | GHS-R inverse agonist |
CAS | 1334782-79-4 |
MW: | 512.7 D |
From 47.00€
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Item number: Cay40149-1
[pGlu4]-Myelin basic protein peptide is a substrate for PKC. It is selectively phosphorylated by PKC over PKA and phosphorylase kinase.Formal Name: 5-oxo-L-prolyl-L-lysyl-L-arginyl-L-prolyl-L-seryl-L-glutaminyl-L-arginyl-L-seryl-L-lysyl-L-tyrosyl-L-leucine, trifluoroacetate salt. Synonyms: [pGlu4]-MBP Peptide....
Keywords: | [pGlu4]-MBP Peptide,... |
Application: | PKC peptide substrate |
MW: | 1373.6 D |
From 34.00€
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Item number: Cay40150-1
Malantide is a synthetic peptide derived from the beta-subunit of human phosphorylase kinase and is a fluorescent substrate for PKA and PKC. Upon phosphorylation by PKA or PKC, the intrinsic tyrosine fluorescence decreases and can be used to quantify PKA and PKC activity. Malantide displays an emission at 302 nm...
Keywords: | L-arginyl-L-threonyl-L-lysyl-L-arginyl-L-serylglycyl-L-seryl-L-valyl-L-tyrosyl-L-alpha-glutamyl-L-prolyl-L-leucyl-L-lysyl-... |
Application: | Fluorescent PKA / PKC substrate |
MW: | 1633.9 D |
From 61.00€
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Item number: Cay40151-1
Myomodulin A is a gastropod neuropeptide. It is found in gastropod ventral lobe neurons, neural elements of the accessory radula closer (ARC) muscle, and penis nerve. Myomodulin A is biosynthesized by ARC motor neurons in A. californica and potentiates motor neuron-elicited contractions of the A. californica buccal...
Keywords: | MMa, MYOMOD1, Pro-Met-Ser-Met-Leu-Arg-Leu-NH2, L-prolyl-L-methionyl-L-seryl-L-methionyl-L-leucyl-L-arginyl-L-leucinamide,... |
Application: | Gastropod neuropeptide |
MW: | 846.1 D |
From 34.00€
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Item number: Cay40170-10
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility:...
Keywords: | L-histidyl-2-methylalanyl-L-alpha-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-valyl-L-s... |
Application: | GLP-1R agonist |
CAS | 2924330-56-1 |
MW: | 4113.6 D |
From 117.00€
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Item number: Cay40231-1
Semaglutide is an agonist of glucagon-like peptide 1 receptor (GLP-1R, EC50 = 6.2 pM in a reporter assay using BHK cells expressing the human receptor). It decreases blood glucose levels in the db/db mouse model of type 2 diabetes (ED50 = 98%. Formulation: (Request formulation change), A solid. Solubility: Methanol:...
Application: | GLP-1R agonist |
CAS | 910463-68-2 |
MW: | 4113.6 D |
From 34.00€
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