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Vascular Endothelial Growth Factor-C (152 amino acids), His Tag, rat recombinant (rrVEGF-C152-His-Sf
Product information "Vascular Endothelial Growth Factor-C (152 amino acids), His Tag, rat recombinant (rrVEGF-C152-His-Sf"
Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. (www.uniprot.org) Produced in Sf9 insect cells, containing 152 amino acids, fused to a His-tag (6x His) at the C-terminus. It has been postulated that VEGF-C is involved in the regulation of the growth and/or differentiation of lymphatic endothelium.