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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Uteroglobin human recombinant produced in E. coli is a single, non-glycosylated polypeptide chain... more
Product information "Uteroglobin, human recombinant"
Uteroglobin human recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 70 amino acids and having a molecular mass of 15.8 kDa. Uteroglobin (SCGB1A1) which belongs to the Secretoglobin (SCGBs) superfamily, is a multifunctional protein that exerts anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. Uteroglobin is involved in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. SCGB1A1 is expressed by Clara cells, the non-ciliated, non-mucous secretory cells predominant in lung bronchioles, and by other epithelia which communicate with the external environment. On top of sequestering pro-inflammatory mediators and carcinogens, Uteroglobin is implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation. SCGB1A1 gene defects are associated with a susceptibility to asthma. The ED50 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5.0 µg/ml, corresponding to a specific activity of > 200 IU/mg.
Keywords: | Clara cell phospholipid-binding protein, CCPBP, Clara cells 10 kDa secretory protein, CC10, Secretoglobin family 1A member 1, Urinary protein 1, UP-1, SCGB1A1, CC10, CCSP, UGB |
Supplier: | Biomol GmbH |
Supplier-Nr: | 97651 |
Properties
Application: | Cell culture |
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
MW: | 15800 D |
Purity: | >98% |
Format: | Lyophilized |
Database Information
UniProt ID : | P11684 | Matching products |
Gene ID | GeneID 7356 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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