Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PKSR030156.100 | 100 µg | - |
7 - 16 business days* |
895.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein Construction: A DNA sequence encoding the rat Serpinf1 (NP_808788.1) (Met1-Thr418) was... more
Product information "SerpinF1 / PEDF Protein (His Tag) (recombinant rat)"
Protein Construction: A DNA sequence encoding the rat Serpinf1 (NP_808788.1) (Met1-Thr418) was expressed with a polyhistidine tag at the C-terminus. Sequence: Met1-Thr418. Fusion tag: C-His Endotoxin: < 1.0 EU per µg protein as determined by the LAL method. Protein function: Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein which has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. PEDF does not inhibit either serine or cysteine proteinases. PEDF exerts diverse physiological activities including anti-angiogenesis, anti-vasopermeability, anti-tumor, and neurotrophic activities. PEDF acts via multiple high affinity ligands and cell receptors. It has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties. PEDF induces macrophages apoptosis and necrosis through the activation of peroxisome proliferator-activated receptor-gamma by which PEDF could modulate inflammatory reactions in septic shock. It balances angiogenesis in the eye and blocks tumor progression.
Keywords: | Alpha-2 antiplasmin, Serpin family F member 1, Serine (Or cysteine) peptidase inhibitor, clade F, member 1, Serine (Or cysteine) peptidase inhibitor, clade F, member 1, isoform CRA_c, Recombinant Rat SerpinF1 / PEDF Protein (His Tag) |
Supplier: | Elabscience |
Supplier-Nr: | E-PKSR030156 |
Properties
Conjugate: | No |
Host: | Human cells |
Species reactivity: | rat |
MW: | 45.9 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K19614 | Matching products |
UniProt ID : | Q80ZA3 | Matching products |
Gene ID | GeneID 287526 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed