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Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The... more
Product information "Macrophage Migration Inhibitory Factor, His Tag, human recombinant (rHuMIF-His-C)"
Pro-inflammatory cytokine. Involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity. (www.uniprot.org) Produced in E.coli as a single, glycosylated, polypeptide chain containing 123 amino acids and fused to a His-tag at C-terminus.
Keywords: | Phenylpyruvate tautomerase, Glycosylation-inhibiting factor, GIF, MMIF, MIF |
Supplier: | Biomol GmbH |
Supplier-Nr: | 95053 |
Properties
Application: | Cell biology studies |
Conjugate: | No |
Expressed in: | E.coli |
Origin: | Human |
MW: | 13500 D |
Purity: | >95% |
Format: | Lyophilized |
Database Information
KEGG ID : | K07253 | Find alternatives |
UniProt ID : | P14174 | Find alternatives |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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