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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Macrophage Inflammatory Protein-5 human recombinant produced in E. coli is a single,... more
Product information "Macrophage Inflammatory protein-5 (CCL15), 68 amino acids, human recombinant (rHuMIP5-68aa)"
Macrophage Inflammatory Protein-5 human recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 68 amino acids and having a molecular mass of 7.4 kDa. CCL15, a new human CC chemokine, was isolated from a human fetal spleen cDNA library. CCL15 cDNA encodes a predicted 113 amino acid (aa) protein containing a putative signal peptide of 21 amino acids that is cleaved to generate a 92 aa residue mature protein. Within the CC family members, human CCL15 shares 45%, 44%, 35%, and 30% aa homology with mouse C10, human MPIF-1, human HCC-1, and mouse MIP-1?, respectively. The gene for MIP-5 is found on chromosome 17 where the genes for most of the human CC chemokines are located. human CCL15 is expressed in T and B lymphocytes, NK cells, monocytes and monocyte-derived dendritic cells. human MIP-5 is chemotactic for T cells and monocytes and has been shown to induce calcium flux in human CCR-1-transfected cells. Measured by its ability to chemoattract THP-1 human acute monocytic leukemia cells. The ED50 for this effect is typically 2 - 4 ng/ml.
Keywords: | Small inducible cytokine A15 precursor, CCL15, Macrophage inflammatory protein 5, MIP-5, MIP5, Chemokine CC-2, HCC-2, NCC-3, MIP- 1 delta, Leukotactin-1, LKN-1, Mrp-2b, C-C motif chemokine 15 |
Supplier: | Biomol GmbH |
Supplier-Nr: | 97623 |
Properties
Application: | Cell culture |
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
MW: | 7400 D |
Purity: | >97% |
Format: | Lyophilized |
Database Information
KEGG ID : | K05511 | Matching products |
UniProt ID : | Q16663 | Matching products |
Gene ID | GeneID 6359 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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