IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively. (www.uniprot.org) Produced in E.coli as a non-glycosylated, polypeptide chain containing 77 amino acids. Interleukin-8 (IL-8) serves as a chemical signal that attracts neutrophils at the site of inflammation.
|Keywords:||IL-8, CXCL8, Monocyte-derived neutrophil chemotactic factor, MDNCF, T-cell chemotactic factor, Neutrophil-activating protein 1, NAP-1, Protein 3-10C, Granulocyte chemotactic protein 1, GCP-1, Monocyte-derived neutrophil-activating peptide, MONAP, Emoctaki|
Handling & Safety
|Shipping:||+20°C (International: +20°C)|
Our products are for laboratory research use only: Not for administration to humans!