Interleukin-23, His Tag, HEK, human recombinant (rHuIL-23-His-HEK)

Interleukin-23, His Tag, HEK, human recombinant (rHuIL-23-His-HEK)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
97503.2 2 µg - -

3 - 10 business days*

70.00€
97503.10 10 µg - -

3 - 10 business days*

180.00€
97503.100 100 µg - -

3 - 10 business days*

-
 
Human recombinant IL-23 produced in HEK 293 cells is a heterodimer (IL23A co-transfected with... more
Product information "Interleukin-23, His Tag, HEK, human recombinant (rHuIL-23-His-HEK)"

Human recombinant IL-23 produced in HEK 293 cells is a heterodimer (IL23A co-transfected with IL12B), containing one polypeptide chain of IL23 protein (19.77kDa) fused with a C-terminal His tag and one polypeptide chain of IL12b-Flag (35.69kDa). IL23 is composed of a subunit of the heterodimeric cytokine IL23 and the p40 subunit of interleukin 12 (IL12B). Interleukin-23 (IL-23) belongs to the IL-12 family and is produced by antigen presenting cells. IL-23 using IL12RB1 and IL-23R (specific for IL-23) can activate STAT and NF-kappaB pathways and stimulate the production of interferon-gamma.). IL-23 is known to take a vital part in the inflammation process and is associated with auto immune diseases. However, unlike IL12, which acts primarily on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.

Keywords: Interleukin 23 alpha subunit p19, Interleukin-12 subunit beta p40, SGRF, IL23P19, IL-23-A, interleukin-six, G-CSF related factor, JKA3 induced upon T-cell activation, interleukin 12B (natural killer cell stimulatory factor 2 cytotoxic lymphocyte maturatio
Supplier: Biomol GmbH
Supplier-Nr: 97503

Properties

Application: Bioassay
Conjugate: No
Expressed in: Human cells
Origin: Human
Purity: >90%
Format: Solution

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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