Il1rn, Recombinant, Rat, aa27-178, His-Tag (Interleukin-1 receptor antagonist protein)

Il1rn also known as Interleukin-1 receptor antagonist protein is a member of the interleukin 1 cytokine family. Il1rn may represent a reservoir of IL-1 inhibitors, released upon cell death, whose function is no limit the pro-inflammatory signals but most prominently by mononuclear phagocytes and keratinocytes. Il1rn is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Source: Recombinant protein corresponding to aa27-178 of rat Il1rn, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~19.8kD, AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHPAGKRP CKMQAFRIWD TNQKTFYLRN NQLIAGYLQG PNTKLEEKID MVPIDFRNVF LGIHGGKLCL SCVKSGDDTK LQLEEVNITD LNKNKEEDKR FTFIRSETGP TTSFESLACP GWFLCTTLEA DHPVSLTNTP KEPCTVTKFY FQEDQ, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.