Human CCL4 / MIP1 beta recombinant protein (Active)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG70422.20	20 µg		-	-	6 - 14 business days*		360.00€
ARG70422.100	100 µg		-	-	6 - 14 business days*		900.00€

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Protein function: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of... more

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Product information "Human CCL4 / MIP1 beta recombinant protein (Active)"

Protein function: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T- cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1- beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. {ECO:0000269, PubMed:10540332, ECO:0000269, PubMed:12070155, ECO:0000269, PubMed:8525373}. [The UniProt Consortium]

Keywords:	CCL4, LAG1, HC21, LAG-1, ACT-2, PAT 744, SIS-gamma, MIP-1-beta, Protein H400, MIP-1-beta(1-69), MIP-1-beta(3-69), C-C motif chemokine 4, Small-inducible cytokine A4, T-cell activation protein 2, G-26 T-lymphocyte-secreted protein, Lymphocyte activation ge
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG70422

Properties

Application:	SDS-PAGE
Conjugate:	No
Species reactivity:	human
Format:	Purified

Database Information

KEGG ID :	K12964 \| Matching products
UniProt ID :	P13236 \| Matching products
Gene ID	GeneID 388372 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	-20°C (International: °C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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