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Human recombinant Granulocyte Colony Stimulating Factor produced in E.coli is a single, non-glycosylated, polypeptide chain containing 175 amino acids and having a molecular mass of 18.8kDa. The Pegylated G-CSF is produced by attaching a 20kDa methoxypolyethylene glycol propionaldehyde (mPEG-ALD) to the N-terminal amino acid of G-CSF giving a total molecular mass of 38.8kDa. GCSF is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Three transcript variants encoding three different isoforms have been found for this gene. Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This csf induces granulocytes.
Keywords: | CSF-3, MGI-1G, GM-CSF beta, Pluripoietin, Filgrastim, Lenograstim, G-CSF, MGC45931, GCSF. |
Supplier: | Biomol GmbH |
Supplier-Nr: | 97555.1 |
Properties
Application: | Cell Culture |
Conjugate: | No |
Expressed in: | E.coli |
Origin: | Human |
MW: | 38800 D |
Purity: | >95% |
Format: | Solution |
Database Information
KEGG ID : | K05423 | Find alternatives |
UniProt ID : | P09919 | Find alternatives |
Gene ID | GeneID 1440 | Find alternatives |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Our products are for laboratory research use only: Not for administration to humans!