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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
CHI-MF-102FGF21-C010 | 10 µg | - | - |
3 - 9 business days* |
226.00€
|
||
CHI-MF-102FGF21-C050 | 50 µg | - | - |
3 - 9 business days* |
523.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Fibroblast growth factor 21 (FGF-21) is a member of the fibroblast growth factor family and has... more
Product information "FGF-21 (mouse) (rec.)"
Fibroblast growth factor 21 (FGF-21) is a member of the fibroblast growth factor family and has been identified as an important regulator of energy metabolism connecting nutrition, growth, reproduction and longevity. FGF-21 lacks the heparin-binding domain of most FGF proteins, allowing its secretion. FGF-21 is abundantly expressed in adipose tissues, liver and pancreas. In adipose tissue, FGF-21 promotes glucose uptake and oxidation and in liver it replenishes on fasting the tissues with fuel on low nutritional supply. It also induces lipolysis and ketogenesis. FGF-21 acts through FGF receptors (FGFR) associated with the auxiliary protein beta-Klotho. Recently, FGF-21 has been reported to interact directly with the brain circadian clock to coordinate activity and reproduction as part of the adaptation to fasting. Due to its multiple functions of normalizing glucose, lipid and energy homeostasis, FGF-21 represents an attractive novel therapy for type 2 diabetes mellitus and obesity.
Keywords: | Fgf21, FGF-21, Fibroblast growth factor 21 |
Supplier: | Chimerigen Laboratories |
Supplier-Nr: | MF-102FGF21 |
Properties
Application: | Bioassays |
Conjugate: | No |
Host: | Human cells |
Species reactivity: | mouse |
MW: | ~23 kD |
Purity: | >90% |
Format: | Lyophilized |
Database Information
KEGG ID : | K22429 | Matching products |
UniProt ID : | Q9JJN1 | Matching products |
Gene ID | GeneID 56636 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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