DKK1 protein (His tag), recombinant mouse

DKK1 protein (His tag), recombinant mouse
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-PDMM100011.20 20 µg -

7 - 16 business days*

426.00€
E-PDMM100011.100 100 µg -

7 - 16 business days*

711.00€
 
Activity: Testing in progress Protein Construction: A DNA sequence encoding the Mouse DKK1... more
Product information "DKK1 protein (His tag), recombinant mouse"
Activity: Testing in progress Protein Construction: A DNA sequence encoding the Mouse DKK1 protein (O54908) (Met1-His272) was expressed with a C-His. Sequence: Met1-His272. Fusion tag: C-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 40 kDa. Protein function: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independe Protein function: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:18524778). Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (PubMed:26206087). Plays a role in limb development, attenuates Wnt signaling in the developing limb to allow normal limb patterning (PubMed:18505822). [The UniProt Consortium]
Keywords: Dkk1, Dkk-1, mDkk-1, Dickkopf-1, Dickkopf-related protein 1, Recombinant Mouse DKK1 protein (His tag)
Supplier: Elabscience
Supplier-Nr: E-PDMM100011

Properties

Conjugate: No
Host: Human cells
Species reactivity: mouse
MW: 29.81 kD
Format: Lyophilized

Handling & Safety

Storage: -80°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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