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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
E-PDEH100112.20 | 20 µg | - |
7 - 16 business days* |
81.00€
|
|||
E-PDEH100112.100 | 100 µg | - |
7 - 16 business days* |
141.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Activity: Testing in progress Protein Construction: A DNA sequence encoding theHuman... more
Product information "DEFbeta2/DEFB2 protein(GST tag), recombinant human"
Activity: Testing in progress Protein Construction: A DNA sequence encoding theHuman DEFbeta2/DEFB2 protein (O15263) (Gly24-Pro64) was expressed with a N-GST. Sequence: Gly24-Pro64. Fusion tag: N-GST Endotoxin: Please contact us for more information. Apparent Molecular Mass: 33 kDa. Protein function: Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells. Protein function: Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria, with highest activity against Gram-negative bacteria (PubMed:9202117, PubMed:10837369). Antimicrobial activity against P.aruginosa seems to be salt-sensitive and is reduced with high salt concentrations greater than 25 mM (PubMed:10837369). Also exhibits antimicrobial activity against the yeast C.albicans (PubMed:9202117, PubMed:10837369, PubMed:30050988). Permeabilizes C.albicans cell membranes via targeting plasma membrane lipid phosphatidylinositol 4,5-bisphosphate (PIP2), thereby leading to cell fragmentation and cell death (PubMed:30050988). Acts as a ligand for C- C chemokine receptor CCR6 (PubMed:10521347, PubMed:20068036). Binds to CCR6 and induces chemotactic activity of CCR6-expressing cells, such as immature dendritic cells and memory T cells (PubMed:10521347, PubMed:20068036). [The UniProt Consortium]
Keywords: | SAP1, BD-2, hBD-2, DEFB4B, DEFB4A, DEFB102, Beta-defensin 2, Defensin, beta 2, Defensin beta 4A, Skin-antimicrobial peptide 1, Recombinant Human DEFbeta2/DEFB2 protein(GST tag) |
Supplier: | Elabscience |
Supplier-Nr: | E-PDEH100112 |
Properties
Conjugate: | No |
Host: | E.coli |
Species reactivity: | human |
MW: | 30.3 kD |
Format: | Lyophilized |
Database Information
KEGG ID : | K21100 | Matching products |
UniProt ID : | O15263 | Matching products |
Gene ID | GeneID 100289462 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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