SB-431542

Item number	Size	Manual	Delivery time	Price
LKT-S0400.1	1 mg	-	3 - 8 business days*	94.00€
LKT-S0400.5	5 mg	-	3 - 8 business days*	324.00€
LKT-S0400.25	25 mg	-	3 - 8 business days*	862.00€

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SB-431542 inhibits activin receptor-like kinases ALK4, ALK5, and ALK7, this inhibition leads to... more

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Product information "SB-431542"

SB-431542 inhibits activin receptor-like kinases ALK4, ALK5, and ALK7, this inhibition leads to inhibition of activin and TGF- signaling with no downstream effects on ERK, JNK, or MAPK. SB-431542 exhibits anti-angiogenic and anticancer activity. In vitro, SB-431542 inhibits proliferation and motility of glioma cells. This compound also induces maturation of dendritic cells through its inhibition of TGF- , increasing IL-12 production and increasing cytotoxic activity of immune cells in vitro.

Supplier:	LKT Laboratories
Supplier-Nr:	S0400

Properties

Application:	ALK4 inhibitor, ALK5 inhibitor, ALK7 inhibitor
MW:	384.39 D
Purity:	>98%
Format:	Solid

Database Information

CAS :	301836-41-9\| Matching products
KEGG ID :	K04674 \| Matching products

Handling & Safety

Storage:	+20°C
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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