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SB-431542
SB-431542

Item number: TGM-T1726-10mg

Description: SB-431542 is an inhibitor of ALK5/TGF-beta type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiation of stem cells. Target: TGF-beta/Smad, ALK. Smiles:...
Keywords: SB 431542
Application: Smad3 phosphorylation inhibitor, TGFBR1/ALK4/ALK7 kinase inhibitor
CAS 301836-41-9
MW: 384.39 D
From 49.00€ *
Review
SB-431542
SB-431542

Item number: LKT-S0400.1

SB-431542 inhibits activin receptor-like kinases ALK4, ALK5, and ALK7, this inhibition leads to inhibition of activin and TGF- signaling with no downstream effects on ERK, JNK, or MAPK. SB-431542 exhibits anti-angiogenic and anticancer activity. In vitro, SB-431542 inhibits proliferation and motility of glioma...
Application: ALK4 inhibitor, ALK5 inhibitor, ALK7 inhibitor
CAS 301836-41-9
MW: 384.39 D
From 99.00€ *
Review