- Search results for 301836-41-9
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2 products were found matching "301836-41-9"!
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Item number: TGM-T1726-10mg
Description: SB-431542 is an inhibitor of ALK5/TGF-beta type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiation of stem cells. Target: TGF-beta/Smad, ALK. Smiles:...
Keywords: | SB 431542 |
Application: | Smad3 phosphorylation inhibitor, TGFBR1/ALK4/ALK7 kinase inhibitor |
CAS | 301836-41-9 |
MW: | 384.39 D |
From 49.00€
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Item number: LKT-S0400.1
SB-431542 inhibits activin receptor-like kinases ALK4, ALK5, and ALK7, this inhibition leads to inhibition of activin and TGF- signaling with no downstream effects on ERK, JNK, or MAPK. SB-431542 exhibits anti-angiogenic and anticancer activity. In vitro, SB-431542 inhibits proliferation and motility of glioma...
Application: | ALK4 inhibitor, ALK5 inhibitor, ALK7 inhibitor |
CAS | 301836-41-9 |
MW: | 384.39 D |
From 99.00€
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