AZD 5597
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
AZD 5597 is a cyclin-dependent kinase 1 (Cdk1) and Cdk2 inhibitor (IC50 = 0.002 µM for both). It... more
Product information "AZD 5597"
AZD 5597 is a cyclin-dependent kinase 1 (Cdk1) and Cdk2 inhibitor (IC50 = 0.002 µM for both). It inhibits LoVo cell proliferation (IC50 = 0.039 µM). In vivo, AZD 5597 (15 mg/kg) reduces tumor volume in an SW620 colon adenocarcinoma mouse xenograft model.Formal Name: [4-[[5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-2-pyrimidinyl]amino]phenyl][(3S)-3-(methylamino)-1-pyrrolidinyl]-methanone. CAS Number: 924641-59-8. Molecular Formula: C23H28FN7O. Formula Weight: 437.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Methanol: Soluble. SMILES: FC1=CN=C(N=C1C2=CN=C(N2C(C)C)C)NC3=CC=C(C(N4CC[C@H](NC)C4)=O)C=C3. InChi Code: InChI=1S/C23H28FN7O/c1-14(2)31-15(3)26-12-20(31)21-19(24)11-27-23(29-21)28-17-7-5-16(6-8-17)22(32)30-10-9-18(13-30)25-4/h5-8,11-12,14,18,25H,9-10,13H2,1-4H3,(H,27,28,29)/t18-/m0/s1. InChi Key: NTSDIJMNXYJJNG-SFHVURJKSA-N.
| Keywords: | [4-[[5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-2-pyrimidinyl]amino]phenyl][(3S)-3-(methylamino)-1-pyrrolidinyl]-methanone |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 38526 |
Properties
| Application: | Cdk1 / Cdk2 inhibitor |
| MW: | 437.5 D |
| Formula: | C23H28FN7O |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 924641-59-8| Matching products |
| KEGG ID : | K02206 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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