2 products were found matching "924641-59-8"!
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AZD-5597
Item number: TGM-T21544-100mg
Description: AZD-5597 ((S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)methanone) is a potent imidazole pyrimidine amide CDK inhibitor. Target: CDK. Smiles: CN[C@H]1CCN(C1)C(=O)c1ccc(Nc2ncc(F)c(n2)-c2cnc(C)n2C(C)C)cc1. References: Jones C D ,...
| Keywords: | (S)-(4-((5-Fluoro-4-(1-isopropyl-2-methyl-1H-imidazol-5-yl)pyrimidin-2-yl)amino)phenyl)(3-(methylamino)pyrrolidin-1-yl)met... |
| CAS | 924641-59-8 |
| MW: | 437.51 D |
From 52.00€
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AZD 5597
Item number: Cay38526-10
AZD 5597 is a cyclin-dependent kinase 1 (Cdk1) and Cdk2 inhibitor (IC50 = 0.002 µM for both). It inhibits LoVo cell proliferation (IC50 = 0.039 µM). In vivo, AZD 5597 (15 mg/kg) reduces tumor volume in an SW620 colon adenocarcinoma mouse xenograft model.Formal Name:...
| Keywords: | [4-[[5-fluoro-4-[2-methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-2-pyrimidinyl]amino]phenyl][(3S)-3-(methylamino)-1-pyrrolidi... |
| Application: | Cdk1 / Cdk2 inhibitor |
| CAS | 924641-59-8 |
| MW: | 437.5 D |
From 161.00€
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