177 products were found matching "K02206"!

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-CDK2/CDK1 (Thr160/Thr161) antibody detects cyclin dependent kinase 2 and cyclin dependent kinase 1 when phosphorylated at their critical threonine residues required for activation. CDK2,...

Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cajal body, Centrosome, Cytoplasm, Cytoskeleton, Endosome, Microtubule organizing center, Nucleus. Positive Control: Jurkat, HEK293T, K-562 or HeLa cells. Chromosome Location: 12q13.2. Protein Function: Serine/threonine-protein kinase...

Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cajal body, Centrosome, Cytoplasm, Cytoskeleton, Endosome, Microtubule organizing center, Nucleus. Positive Control: Jurkat, HEK293T, K-562 or HeLa cells. Chromosome Location: 12q13.2. Protein Function: Serine/threonine-protein kinase...

Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cajal body, Centrosome, Cytoplasm, Cytoskeleton, Endosome, Microtubule organizing center, Nucleus. Positive Control: Jurkat, HEK293T, K-562 or HeLa cells. Chromosome Location: 12q13.2. Protein Function: Serine/threonine-protein kinase...

Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cajal body, Centrosome, Cytoplasm, Cytoskeleton, Endosome, Microtubule organizing center, Nucleus. Positive Control: Jurkat, HEK293T, K-562 or HeLa cells. Chromosome Location: 12q13.2. Protein Function: Serine/threonine-protein kinase...

CDK2(cyclin dependent kinase 2) Homo sapiens This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity...

GW 8510 is an inhibitor of cyclin-dependent kinase 2 (Cdk2) and Cdk5 (IC50s = 3, 3, and 7 nM for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk5/p25 complexes, respectively). It is selective for Cdk2 and Cdk5 over Cdk1/cyclin B, Cdk4/cyclin D, Cdk7/cyclin H, and Cdk9/cyclin T (IC50s = 49, 139, 317, and 543 nM, respectively)....

A Cdk2 inhibitor (IC50 = 0.044 µM), selective for Cdk2 over Cdk1, Cdk4, Cdk7, and Cdk9 at 100 µM. Formulation: A solid. InChI: InChI=1S/C23H18N6O2S/c24-32(30,31)19-11-9-18(10-12-19)27-23-28-20(21-22(29-23)26-14-25-21)17-8-4-7-16(13-17)15-5-2-1-3-6-15/h1-14H,(H2,24,30,31)(H2,25,26,27,28,29). InChIKey:...

Alsterpaullone is a derivative of kenpaullone (Cay-10010239), an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3beta (GSK3beta). With slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E,...

PF-06873600 is an inhibitor of cyclin-dependent kinase 2 (Cdk2), Cdk4, and Cdk6 (Kis = 0.13, 1.25, and 0.11 nM, respectively). It is selective for these CDKs over Cdk1 and Cdk9 (Kis = 4.5 and 19.6 nM, respectively). PF-06873600 inhibits the phosphorylation of RB transcriptional corepressor 1 (RB1) in, and the...

Protein function: Serine/threonine-protein kinase involved in the control of the cell cycle, essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F...

Olomoucine II is an inhibitor of cyclin-dependent kinases (CDKs, IC50s = 7.6, 0.1, 19.8, 0.45, and 0.06 µM for Cdk1, -2, -4, -7, and -9, respectively). It is selective for CDKs over 10 additional kinases (IC50s = >100 µM for all) but does inhibit ERK2 (IC50 = 32 µM) and the ATP-binding cassette transporter B1...