182 products were found matching "K02206"!

Cdk2 peptide substrate is an optimal peptide substrate of Cdk2. It binds across the Cdk2 catalytic site when in complex with Cdk2 phosphorylated at T160 and cyclin A3. Cdk2 peptide substrate has been used in enzyme assays for Cdk2 activity.. SMILES:...

(S)-PHA-533533 is an inhibitor of cyclin-dependent kinase 2 (Cdk2)/cyclin A, Cdk2/cyclin E, Cdk5/p25, and Cdk1/cyclin B complexes and glycogen synthase kinase 3beta (GSK3beta, IC50s = 37, 55, 65, 208, and 732 nM, respectively, in cell-free assays). It selectively inhibits these complexes and GSK3beta over the...

Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cajal body, Centrosome, Cytoplasm, Cytoskeleton, Endosome, Microtubule organizing center, Nucleus. Positive Control: Jurkat, HEK293T, K-562 or HeLa cells. Chromosome Location: 12q13.2. Protein Function: Serine/threonine-protein kinase...

Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cajal body, Centrosome, Cytoplasm, Cytoskeleton, Endosome, Microtubule organizing center, Nucleus. Positive Control: Jurkat, HEK293T, K-562 or HeLa cells. Chromosome Location: 12q13.2. Protein Function: Serine/threonine-protein kinase...

Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Cajal body, Centrosome, Cytoplasm, Cytoskeleton, Endosome, Microtubule organizing center, Nucleus. Positive Control: Jurkat, HEK293T, K-562 or HeLa cells. Chromosome Location: 12q13.2. Protein Function: Serine/threonine-protein kinase...

Formulation: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml. Cellular Localization: Cajal body, Centrosome, Cytoplasm, Cytoskeleton, Endosome, Microtubule organizing center, Nucleus. Positive Control: Jurkat, HEK293T, K-562 or HeLa cells. Chromosome Location: 12q13.2. Protein Function: Serine/threonine-protein kinase...

CDK2(cyclin dependent kinase 2) Homo sapiens This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-CDK2/CDK1 (Thr160/Thr161) antibody detects cyclin dependent kinase 2 and cyclin dependent kinase 1 when phosphorylated at their critical threonine residues required for activation. CDK2,...

GW 8510 is an inhibitor of cyclin-dependent kinase 2 (Cdk2) and Cdk5 (IC50s = 3, 3, and 7 nM for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk5/p25 complexes, respectively). It is selective for Cdk2 and Cdk5 over Cdk1/cyclin B, Cdk4/cyclin D, Cdk7/cyclin H, and Cdk9/cyclin T (IC50s = 49, 139, 317, and 543 nM, respectively)....

Alsterpaullone is a derivative of kenpaullone (Cay-10010239), an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3beta (GSK3beta). With slightly improved potency over kenpaullone, alsterpaullone selectively inhibits Cdk1/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E,...

PF-06873600 is an inhibitor of cyclin-dependent kinase 2 (Cdk2), Cdk4, and Cdk6 (Kis = 0.13, 1.25, and 0.11 nM, respectively). It is selective for these CDKs over Cdk1 and Cdk9 (Kis = 4.5 and 19.6 nM, respectively). PF-06873600 inhibits the phosphorylation of RB transcriptional corepressor 1 (RB1) in, and the...

Protein function: Serine/threonine-protein kinase involved in the control of the cell cycle, essential for meiosis, but dispensable for mitosis. Phosphorylates CTNNB1, USP37, p53/TP53, NPM1, CDK7, RB1, BRCA2, MYC, NPAT, EZH2. Triggers duplication of centrosomes and DNA. Acts at the G1-S transition to promote the E2F...