7-Benzyloxy-4-(trifluoromethyl)coumarin
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Larger quantity required? Request bulk
7-Benzyloxy-4-(trifluoromethyl)coumarin (BFC) is a fluorogenic substrate for the cytochrome P450... more
Product information "7-Benzyloxy-4-(trifluoromethyl)coumarin"
7-Benzyloxy-4-(trifluoromethyl)coumarin (BFC) is a fluorogenic substrate for the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A. Upon enzymatic cleavage by CYP1A2 or CYP3A, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP1A2 and CYP3A activity. HFC displays excitation/emission maxima of 410/510 nm, respectively.Formal Name: 7-(phenylmethoxy)-4-(trifluoromethyl)-2H-1-benzopyran-2-one. CAS Number: 220001-53-6. Synonyms: BFC. Molecular Formula: C17H11F3O3. Formula Weight: 320.3. Purity: >95%. Emission: 510 nm. Excitation: 410 nm. Formulation: (Request formulation change), A solid. Solubility: DMF: 3 mg/ml, DMSO: 1 mg/ml, Ethanol: insol, PBS (pH 7.2): insol. SMILES: O=C1OC2=C(C(C(F)(F)F)=C1)C=CC(OCC3=CC=CC=C3)=C2. InChi Code: InChI=1S/C17H11F3O3/c18-17(19,20)14-9-16(21)23-15-8-12(6-7-13(14)15)22-10-11-4-2-1-3-5-11/h1-9H,10H2. InChi Key: WVKLERKKJXUPIK-UHFFFAOYSA-N.
| Keywords: | BFC, 7-(phenylmethoxy)-4-(trifluoromethyl)-2H-1-benzopyran-2-one |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 35721 |
Properties
| Application: | Fluorogenic CYP1A2 / CYP3A substrate |
| MW: | 320.3 D |
| Formula: | C17H11F3O3 |
| Purity: | >95% |
| Format: | Solid |
Database Information
| CAS : | 220001-53-6| Matching products |
| KEGG ID : | K07409 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H312, H332 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P312, P321, P330, P361+364, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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