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7-BFC
7-BFC

Item number: TGM-T117521-100mg

Description: 7-BFC (7-Benzyloxy-4-(trifluoromethyl)coumarin) is a coumarin-like fluorescent substrate that serves as a biomarker for cytochrome P 450 and can be used to study CYP isoforms and cytochrome P 450 metabolism. Target: P450. Smiles: FC(F)(F)c1cc(=O)oc2cc(OCc3ccccc3)ccc12. References: A B Renwick, et al....
Keywords: 7-Benzyloxy-4-(trifluoromethyl)coumarin, Y040-0031
Application: Fluorogenic CYP1A2 / CYP3A substrate
CAS 220001-53-6
MW: 320.26 D
From 42.00€ *
Review
7-Benzyloxy-4-(trifluoromethyl)coumarin
7-Benzyloxy-4-(trifluoromethyl)coumarin

Item number: Cay35721-10

7-Benzyloxy-4-(trifluoromethyl)coumarin (BFC) is a fluorogenic substrate for the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A. Upon enzymatic cleavage by CYP1A2 or CYP3A, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP1A2 and CYP3A activity. HFC displays...
Keywords: BFC, 7-(phenylmethoxy)-4-(trifluoromethyl)-2H-1-benzopyran-2-one
Application: Fluorogenic CYP1A2 / CYP3A substrate
CAS 220001-53-6
MW: 320.3 D
From 102.00€ *
Review
7-Benzyloxy-4-trifluoromethycoumarin
7-Benzyloxy-4-trifluoromethycoumarin

Item number: CDX-B0299-M050

7-Benzyloxy-4-trifluoromethylcoumarin is a fluorescent substrate for cytochrome P450 family members CYP1A2, CYP3A4 and potentially others. Has been used in high-throughput screens in fluorometric p450 activity assays and is metabolized to the fluorescent metabolite 7-Hydroxy-4-trifluoromethylcoumarin (HFC) with...
Keywords: BFC
Application: Fluoregenic CYP1A2 / CYP3A4 substrate
CAS 220001-53-6
MW: 320,3 D
From 307.00€ *
Review