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Item number: Cay35721-10

7-Benzyloxy-4-(trifluoromethyl)coumarin (BFC) is a fluorogenic substrate for the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A. Upon enzymatic cleavage by CYP1A2 or CYP3A, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP1A2 and CYP3A activity. HFC displays...

Keywords:	BFC, 7-(phenylmethoxy)-4-(trifluoromethyl)-2H-1-benzopyran-2-one
Application:	Fluorogenic CYP1A2 / CYP3A substrate
CAS	220001-53-6
MW:	320.3 D

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7-Benzyloxy-4-trifluoromethycoumarin

Item number: CDX-B0299-M050

7-Benzyloxy-4-trifluoromethylcoumarin is a fluorescent substrate for cytochrome P450 family members CYP1A2, CYP3A4 and potentially others. Has been used in high-throughput screens in fluorometric p450 activity assays and is metabolized to the fluorescent metabolite 7-Hydroxy-4-trifluoromethylcoumarin (HFC) with...

Keywords:	BFC
Application:	Fluoregenic CYP1A2 / CYP3A4 substrate
CAS	220001-53-6
MW:	320,3 D

From 307.00€ *

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