64 products were found matching "K07409"!

Isoimperatorin is a natural furanocoumarin that can be isolated from a variety of plant parts. It inhibits cytochrome P450 (CYP) isoform 1A activity, in particular blocking hepatic ethoxyresorufin O-dealkylase activity. Through its effects on CYP1A, isoimperatorin reduces the metabolism of polycyclic aromatic...

Furafylline is a selective inhibitor of human cytochrome P450 (CYP)1A2 (IC50 = 0.07 µM), demonstrating little effect on other CYP isoforms including 2D1, 2C, 3A, or 1A1. It was originally introduced as a bronchodilator with extended duration compared to theophylline, but then subsequently reported to inhibit the...

Naringenin-7-O-beta-D-glucuronide is a metabolite of the flavonoid naringenin (Cay-14173). It is formed from naringenin primarily by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1, UGT1A3, UGT1A6, and UGT1A9.Formal Name: 3,4-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-2H-1-benzopyran-7-yl,...

6-hydroxy Warfarin is a metabolite of (+)-warfarin (Cay-13526), which is a weaker vitamin K antagonist than (-)-warfarin (Cay-13531). Both isomers of warfarin are metabolized by the cytochrome P450 isoform 2C9 (CYP2C9), however, stereoselective metabolism also occurs, with CYP1A1 and CYP1A2 primarily responsible for...

A human CYP1A enzyme activity inhibitor natural flavonoid. Diosmetin has antimutagenic and anti allergic characters.

3-Cyano-7-ethoxycoumarin is a fluorogenic probe that acts as a substrate for the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2 and is metabolized to a lesser extent by CYP2D6 and CYP2C19. It is metabolized to 3-cyano-7-hydroxycoumarin, which displays excitation/emission maxima of 408/450 nm, respectively....

In ascites with 0.09% sodium azide. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. CYP1A2 (Cytochrome P450, Subfamily I, Polypeptide 2) is a member of the cytochrome P450 mixed-function oxidase system and is involved in the metabolism of xenobiotics in the body. CYP1A2 is a member of the cytochrome P450 superfamily of enzymes. In humans, the...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Cytochrome P450 1A2 Protein function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway....

Stiripentol is a third-generation antiepileptic compound. It is a positive allosteric modulator of GABAA receptors, potentiating GABA-mediated activation to a greater extent in receptors expressing alpha3 subunits and to a lower extent in those containing beta1 or epsilon subunits. It also inhibits GABA reuptake in...