Other Cell-Based Assays

The kit uses a proprietary lysotropic dye that selectively accumulates in lysosomes probably vial the lysosome pH gradient. The dye easily permeates intact live cells, and trapped in lysosomes after it gets into cells.

This particular kit is designed to uniformly label live cells in blue fluorescence for the studies that require the fluorescent tag molecules retained inside cells for relatively longer time.

Membrane potential is the difference in voltage between the interior and exterior of a cell. The membrane potential allows a cell to function as a battery, providing power to operate a variety of molecular devices embedded in the membrane. In electrically excitable cells such as neurons, membrane potential is used...

Cayman's Early Apoptosis Detection Assay Kit employs FITC-conjugated annexin V as a probe for phosphatidylserine (PS) on the outer membrane of apoptotic cells, TMRE as a probe for DeltaPsim, DAPI as an indicator of membrane permeability/cell viability, and TO-PRO(R)-3 to indicate the selective permeability of...

Membrane potential is the difference in voltage between the interior and exterior of a cell. The membrane potential allows a cell to function as a battery, providing power to operate a variety of molecular devices embedded in the membrane. In electrically excitable cells such as neurons, membrane potential is used...

Our Cell Explorer(TM) Live Cell Tracking Kit uses a proprietary orange fluorescent dye that gets enhanced fluorescence upon entering into live cells. The dye is a hydrophobic compound that easily permeates intact live cells. The hydrolysis of the weakly fluorescent substrate by intracellular esterases generates a...

The kit uses a proprietary lysotropic dye that selectively accumulates in lysosomes probably vial the lysosome pH gradient. The dye easily permeates intact live cells, and trapped in lysosomes after it gets into cells.

This complete kit is designed to label F-actins of fixed cells in green fluorescence. The kit uses a blue fluorescent phalloidin conjugate that is selectively bound to F-actins.

Obesity is a growing concern worldwide and has reached epidemic proportions in the United States. It is a risk factor in many major chronic diseases that afflict our society, including cardiovascular disease, diabetes mellitus, and cancer. In recent years, numerous studies have focused on identifying the mechanism...

Steatosis, also known as fatty liver, is a pathological process characterized by abnormal accumulation of lipid within cells. While simple steatosis may not be associated with significant impairment of liver function, excessive fat accumulation can lead to cirrhosis and even liver failure. The molecular mechanisms...

Mammalian soluble epoxide hydrolase (sEH) is a member of the alpha/beta-hydrolase fold family of enzymes that catalyze the hydrolysis of exogenous and endogenous epoxides to vicinal diols. sEH is a homodimer consisting of two domains. The C-terminal domain is responsible for the epoxide hydrolase activity while the...

Glutathione (GSH) is the most prevalent low molecular-weight tripeptide thiol in animal cells. It serves as a primary cellular anti-oxidant and plays a fundamental role in the elimination of environmental toxins. During early apoptosis, cells may exclude GSH, causing a decrease in intracellular GSH levels. The...